862913-13-1
Chemical Structure
AMC Arachidonoyl Amide
Synonym(s): AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide
- CAS No.: 862913-13-1
- Formula:C30H39NO3
- Molecular Weight:461.64
IUPAC Name: (5Z,8Z,11Z,14Z)-N-(4-methyl-2-oxo-2H-chromen-7-yl)icosa-5,8,11,14-tetraenamide
InChIKey: IQPBUDMTXHWSHB-ZKWNWVNESA-N
SMILES: CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)=O
Biological Activity: AMC Arachidonoyl Amide (AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide) is a fluorescent fatty acid amide substrate used to detect fatty acid amide hydrolase (FAAH) activity. AMC Arachidonoyl Amide releases 7-amino-4-methylcoumarin (AMC) upon hydrolysis by FAAH, producing fluorescence at Ex 360 nm/Em 465 nm, thereby allowing rapid determination of FAAH activity using a cuvette or microplate fluorometer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
AMC Arachidonoyl Amide | 99.5% | AMC Arachidonoyl Amide (AMC-AA; 7-Amino-4-methyl coumarin-arachidonamide) is a fluorescent fatty acid amide substrate used to detect fatty acid amide hydrolase (FAAH) activity. AMC Arachidonoyl Amide releases 7-amino-4-methylcoumarin (AMC) upon hydrolysis by FAAH, producing fluorescence at Ex 360 nm/Em 465 nm, thereby allowing rapid determination of FAAH activity using a cuvette or microplate fluorometer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Tan YJ, et al. Cistanoside F acts as a Monoacylglycerol Lipase inhibitor that synergizes the anti-tumor effect of 2-Arachidonoyl Glycerol on Bladder cancer. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2025 Sep;145:157046. [Content Brief]
- [2]. Cravatt BF, et al. Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature. 1996 Nov 07;384(6604):83-7. [Content Brief]
