86383-32-6
Chemical Structure
5-Hydroxy Propafenone hydrochloride
Synonym(s): GPV-129 hydrochloride
- CAS No.: 86383-32-6
- Formula:C21H28ClNO4
- Molecular Weight:393.90
IUPAC Name: 1-(5-hydroxy-2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one hydrochloride
InChIKey: FAYLNKVZLXBDBE-UHFFFAOYSA-N
SMILES: [H]Cl.O=C(C1=CC(O)=CC=C1OCC(O)CNCCC)CCC2=CC=CC=C2
Biological Activity: 5-Hydroxy Propafenone (hydrochloride) is an inhibitor of cardiac myocyte repolarizing currents. 5-Hydroxy Propafenone is an active metabolite of propafenone. 5-Hydroxy Propafenone (hydrochloride) inhibits transient outward potassium current (Ito) in isolated human arterial myocytes with an IC50 of 1.5 μM. 5-Hydroxy Propafenone (hydrochloride) is potent Ito inhibitor in neonatal rat ventricular myocytes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
5-Hydroxy Propafenone hydrochloride | 5-Hydroxy Propafenone (hydrochloride) is an inhibitor of cardiac myocyte repolarizing currents. 5-Hydroxy Propafenone is an active metabolite of propafenone. 5-Hydroxy Propafenone (hydrochloride) inhibits transient outward potassium current (Ito) in isolated human arterial myocytes with an IC50 of 1.5 μM. 5-Hydroxy Propafenone (hydrochloride) is potent Ito inhibitor in neonatal rat ventricular myocytes. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
5-Hydroxy Propafenone-d6 hydrochloride | 5-Hydroxy Propafenone-d6 hydrochloride is deuterated labeled 5-Hydroxy Propafenone. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
