870677-05-7
Chemical Structure
(S)-DMAPT
Synonym(s): (S)-Dimethylamino Parthenolide
- CAS No.: 870677-05-7
- Formula:C17H27NO3
- Molecular Weight:293.40
IUPAC Name: (1aR,7aS,8S,10aS,10bR,Z)-8-((dimethylamino)methyl)-1a,5-dimethyl-2,3,6,7,7a,8,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-9(1aH)-one
InChIKey: UJNSFDHVIBGEJZ-CMRIBGNTSA-N
SMILES: C[C@]12[C@@](O2)([H])[C@]3([H])[C@](CC/C(C)=C\CC1)([H])[C@H](C(O3)=O)CN(C)C
Biological Activity: (S)-DMAPT ((S)-Dimethylamino Parthenolide) is a sesquiterpene lactone with radioprotective and radiation-mitigating effects. (S)-DMAPT alleviates radiation-induced bladder fibrosis and fibrosis markers in the lungs and bladder. (S)-DMAPT alleviates radiation-induced oligospermia, colorectal tissue senescence, and testicular senescence. (S)-DMAPT prevents radiation-induced skin damage[1].
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(S)-DMAPT | (S)-DMAPT ((S)-Dimethylamino Parthenolide) is a sesquiterpene lactone with radioprotective and radiation-mitigating effects. (S)-DMAPT alleviates radiation-induced bladder fibrosis and fibrosis markers in the lungs and bladder. (S)-DMAPT alleviates radiation-induced oligospermia, colorectal tissue senescence, and testicular senescence. (S)-DMAPT prevents radiation-induced skin damage. | |||||||||||||||||||||
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