875142-27-1
Chemical Structure
HW12
- CAS No.: 875142-27-1
- Formula:C72H89N19O17
- Molecular Weight:1492.59
InChIKey: XJSXRAMOPQFXIT-QZXUKGOESA-N
SMILES: O=C([C@H]1N(CCC1)C([C@@H](NC([C@H]([C@H](O)C)NC([C@H]2N(CCC2)C([C@@H](NC([C@H](C)NC([C@H](CC3=CC=C(C=C3)O)NC([C@H]4N(CCC4)C([C@@H](NC([C@@H](N)CC5=CN=CN5)=O)CC6=CC=C(C=C6)O)=O)=O)=O)=O)CC7=CN=CN7)=O)=O)=O)CC8=CN=CN8)=O)N[C@@H](CO)C(N[C@H](C(O)=O)CC9=CNC%10=CC=CC=C9%10)=O
Biological Activity: HW12 is a scrambled peptide control with no EGFR ligand activity. HW12 shows low cellular uptake levels in EGFR-positive cells. HW12 exerts weak growth inhibitory effects on pancreatic cancer. HW12 serves as a scrambled peptide control for EGFR-targeted GE11 (HY-P10128)-conjugated mixed micelles. HW12 can be used in pancreatic cancer research[1].
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HW12 | HW12 is a scrambled peptide control with no EGFR ligand activity. HW12 shows low cellular uptake levels in EGFR-positive cells. HW12 exerts weak growth inhibitory effects on pancreatic cancer. HW12 serves as a scrambled peptide control for EGFR-targeted GE11 (HY-P10128)-conjugated mixed micelles. HW12 can be used in pancreatic cancer research. | |||||||||||||||||||||
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