878983-38-1
878983-38-1
Chemical Structure
AKOS-22
- CAS No.: 878983-38-1
- Formula:C22H21ClF3N3O3
- Molecular Weight:467.87
IUPAC Name: 1-(4-chlorophenyl)-3-(4-((4-(trifluoromethoxy)phenyl)amino)piperidin-1-yl)pyrrolidine-2,5-dione
InChIKey: ZZVCWIMICOFQNJ-UHFFFAOYSA-N
SMILES: O=C(C(N1CCC(NC2=CC=C(OC(F)(F)F)C=C2)CC1)C3)N(C4=CC=C(Cl)C=C4)C3=O
Biological Activity: AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AKOS-22 | 99.23% | AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction. | ||||||||||||||||||||
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AKOS-22 (Standard) | ≥98% | AKOS-22 (Standard) is the analytical standard of AKOS-22 (HY-111217). This product is intended for research and analytical applications. AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction. | ||||||||||||||||||||
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