87958-67-6
87958-67-6
Chemical Structure
CGP52608
- CAS No.: 87958-67-6
- Formula:C8H12N4OS2
- Molecular Weight:244.34
IUPAC Name: (E)-2-(3-allyl-4-oxothiazolidin-2-ylidene)-N-methylhydrazine-1-carbothioamide
InChIKey: DDYJDIHOSRTMSE-DHZHZOJOSA-N
SMILES: C=CCN1/C(SCC1=O)=N\NC(NC)=S
Biological Activity: CGP52608 is a selective agonist for the RZR/ROR receptor, known for its anti-tumor activity, and has almost no affinity for the cell surface G-protein coupled melatonin receptor. CGP52608 can inhibit the growth of mouse 16/C breast cancer cells. CGP52608 can induce the formation of vesicles in diatoms[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CGP52608 | 99.6% | CGP52608 is a selective agonist for the RZR/ROR receptor, known for its anti-tumor activity, and has almost no affinity for the cell surface G-protein coupled melatonin receptor. CGP52608 can inhibit the growth of mouse 16/C breast cancer cells. CGP52608 can induce the formation of vesicles in diatoms. | ||||||||||||||||||||
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References
- [1]. S T Tslm, et al. CGP 52608-induced cyst formation in dinoflagellates: possible involvement of a nuclear receptor for melatonin. J Pineal Res. 1996 Sep;21(2):101-7. [Content Brief]
- [2]. Katarzyna Winczyk, et al. Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells. Neuro Endocrinol Lett. 2006 Jun;27(3):351-4. [Content Brief]
