88441-08-1
88441-08-1
Chemical Structure
2C-CN hydrochloride
- CAS No.: 88441-08-1
- Formula:C11H15ClN2O2
- Molecular Weight:242.70
IUPAC Name: 4-(2-aminoethyl)-2,5-dimethoxybenzonitrile hydrochloride
InChIKey: UTIJAZMOSJQGGJ-UHFFFAOYSA-N
SMILES: Cl.N#CC=1C=C(OC)C(=CC1OC)CCN
Biological Activity: 2C-CN hydrochloride is a selective agonist of the 5-HT2A Receptor. 2C-CN hydrochloride derivative NBOH-2C-CN hydrochloride can block risperidone-induced hypothermia in gerbils and enhance rigidity behavior in mice after predictable fear conditioning. 2C-CN hydrochloride can be used in studies related to thermoregulation and anxiety disorders[1][2][3].
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2C-CN hydrochloride | 2C-CN hydrochloride is a selective agonist of the 5-HT2A Receptor. 2C-CN hydrochloride derivative NBOH-2C-CN hydrochloride can block risperidone-induced hypothermia in gerbils and enhance rigidity behavior in mice after predictable fear conditioning. 2C-CN hydrochloride can be used in studies related to thermoregulation and anxiety disorders. | |||||||||||||||||||||
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References
- [1]. Yang GE, et al. Risperidone Treatment after Transient Ischemia Induces Hypothermia and Provides Neuroprotection in the Gerbil Hippocampus by Decreasing Oxidative Stress. International journal of molecular sciences. 2019 Sep 18;20(18):4621. [Content Brief]
- [2]. Hessel M, et al. Stimulation of 5-HT receptors in anterodorsal BNST guides fear to predictable and unpredictable threat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2020 Oct;39:56-69. [Content Brief]
- [3]. Pottie E, et al. Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT Receptor Agonists. ACS chemical neuroscience. 2023 Aug 02;14(15):2727-2742. [Content Brief]
