88795-32-8
88795-32-8
Chemical Structure
Z-Pro-prolinal
Synonym(s): N-Benzyloxycarbonyl-L-prolyl-L-prolinal
- CAS No.: 88795-32-8
- Formula:C18H22N2O4
- Molecular Weight:330.38
IUPAC Name: benzyl (S)-2-((S)-2-formylpyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
InChIKey: ORZXYSPOAVJYRU-HOTGVXAUSA-N
SMILES: O=C[C@H]1N(C([C@H]2N(C(OCC3=CC=CC=C3)=O)CCC2)=O)CCC1
Biological Activity: Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) is a specific, orally active prolyl endopeptidase (PREP) inhibitor with an IC50 of 0.4 nM for porcine PREP[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Z-Pro-prolinal | 99.9% | Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) is a specific, orally active prolyl endopeptidase (PREP) inhibitor with an IC50 of 0.4 nM for porcine PREP. | ||||||||||||||||||||
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References
- [1]. Tsuru D, et al. Thiazolidine derivatives as potent inhibitors specific for prolyl endopeptidase. J Biochem. 1988;104(4):580-586. [Content Brief]
- [2]. Kilpeläinen TP, et al. The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy. Biomed Pharmacother. 2020;128:110253. [Content Brief]
- [3]. Miura N, et al. Increase in the septal vasopressin content by prolyl endopeptidase inhibitors in rats. Neurosci Lett. 1995;196(1-2):128-130. [Content Brief]
