89196-78-1
Chemical Structure
Pyruvic acid-13C2-1 sodium
Synonym(s): Sodium 2-oxopropanoate-13C2; Acetylformic acid-13C2-1 sodium
- CAS No.: 89196-78-1
- Formula:C13C2H3NaO3
- Molecular Weight:112.03
IUPAC Name: sodium 3-hydroxybutanoate-1-13C
InChIKey: DAEPDZWVDSPTHF-AWQJXPNKSA-M
SMILES: [13CH3][13C](C(O[Na])=O)=O
Biological Activity: 2-Oxopropanoate-13C2 (sodium) is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Pyruvic acid-13C2-1 sodium | 99.0% | 2-Oxopropanoate-13C2 (sodium) is the 13C labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS. | ||||||||||||||||||||
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Pyruvic acid sodium (Standard) | 99.98% | Sodium 2-oxopropanoate (Standard) is the analytical standard of Sodium 2-oxopropanoate. This product is intended for research and analytical applications. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS. | ||||||||||||||||||||
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Pyruvic acid-13C3 sodium | 99.61% | Sodium 2-oxopropanoate-13C3 is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS. | ||||||||||||||||||||
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Pyruvic acid-13C-1 sodium | 98.90% | Sodium 2-oxopropanoate-13C is the 13C labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS. | ||||||||||||||||||||
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Pyruvic acid-13C sodium | 99.18% | Pyruvic acid-13C (sodium) is the 13C-labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. | ||||||||||||||||||||
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Pyruvic acid-d3 sodium | 98.4% | Sodium 2-oxopropanoate-d3 is the deuterium labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS. | ||||||||||||||||||||
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Pyruvic acid sodium | 99.86% | Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS. | ||||||||||||||||||||
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Acetoacetic acid sodium | 98.0% | Acetoacetic acid sodium is an oxidative stress inducer that affects the antioxidant enzyme system and lipoprotein metabolism. Acetoacetic acid sodium induces oxidative stress by decreasing the mRNA expression and activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), increasing MDA content, and inhibiting very low density lipoprotein (VLDL) assembly by downregulating apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR), leading to triglyceride (TG) accumulation in hepatocytes. Acetoacetic acid sodium can be used to study metabolic diseases. | ||||||||||||||||||||
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(R)-Sodium α-ketoisocaproate-d3 | (R)-Sodium α-ketoisocaproate-d3 is the deuterium labeled (R)-Sodium α-ketoisocaproate. | |||||||||||||||||||||
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Sodium 2-oxobutanoate-13C4,d2 hydrate | Sodium 2-oxobutanoate-13C4,d2 (hydrate) is the deuterium and 13C labeled Sodium 2-oxobutanoate hydrate. | |||||||||||||||||||||
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Sodium 2-oxobutanoate-13C4 | 99.5% | Sodium 2-oxobutanoate-13C4 is the 13C labeled Sodium 2-oxobutanoate. | ||||||||||||||||||||
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Sodium 3-methyl-2-oxobutanoate | 99.95% | Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli. | ||||||||||||||||||||
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Sodium 3-methyl-2-oxobutanoate (Standard) | ≥98% | Sodium 3-methyl-2-oxobutanoate (Standard) is the analytical standard of Sodium 3-methyl-2-oxobutanoate. This product is intended for research and analytical applications. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli. | ||||||||||||||||||||
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Sodium 3-methyl-2-oxobutanoate-13C4,d3 | Sodium 3-methyl-2-oxobutanoate-13C4,d3 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli. | |||||||||||||||||||||
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Sodium 3-methyl-2-oxobutanoate-13C,d4 | Sodium 3-methyl-2-oxobutanoate-13C,d4 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli. | |||||||||||||||||||||
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Sodium 3-methyl-2-oxobutanoate-13C5 | 99.95% | Sodium 3-methyl-2-oxobutanoate-13C5 is the 13C labeled Sodium 3-methyl-2-oxobutanoate. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli. | ||||||||||||||||||||
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Sodium 3-Methyl-2-oxobutanoic acid-13C2 | 99.90% | 3-Methyl-2-oxobutanoic acid-13C2 is the 13C labeled Sodium 3-methyl-2-oxobutanoate. Sodium 3-methyl-2-oxobutanoate is a precursor of pantothenic acid in Escherichia coli. | ||||||||||||||||||||
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3-Methyl-2-oxobutanoic acid-13C4,d4 sodium | 98.0% | Sodium 3-methyl-2-oxobutanoate-13C4,d4 is the deuterium and 13C labeled Sodium 3-methyl-2-oxobutanoate. | ||||||||||||||||||||
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Methyl pyruvate | 99.81% | Methyl pyruvate is a p53/p21 axis inhibitor, intrinsic apoptosis inhibitor, cytotoxic agent, ATP production enhancer, proteasome function restorer, TDP-43 localization normalizer, ATP-sensitive potassium (K+ATP) channel inhibitor, depolarizer, and insulin secretagogue.Methyl pyruvate turns off apoptotic pathways, induces cancer cell death, acts as a substrate for dimeric dihydrodiol dehydrogenase, enhances TCA cycle activity, rescues proteasome impairment and TDP-43 mislocalization, inhibits K+ATP channels independent of ATP, depolarizes pancreatic β-cell membranes, modulates insulin secretion, and enters pancreatic β-cell mitochondria via a specific transporter.Methyl pyruvate can be used for the research of lung adenocarcinoma, ovarian clear cell adenocarcinoma, breast adenocarcinoma, amyotrophic lateral sclerosis, and type II diabetes. | ||||||||||||||||||||
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Pyruvic acid-1-13C-2 sodium | 99% | Pyruvic acid-13C-2 (sodium) is the 13C labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. | ||||||||||||||||||||
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Pyruvic acid-13C,d4 | 99.80% | Pyruvic acid-13C,d4 is the deuterium and 13C labeled Pyruvic acid. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats. | ||||||||||||||||||||
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Ethyl pyruvate-d3 | Ethyl pyruvate-d3 is the deuterium labeled Ethyl pyruvate. Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent. | |||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. S Nemoto, et al. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol. 2000 Oct;20(19):7311-8. [Content Brief]
- [3]. W Zhao, et al. Fructose induced deactivation of antioxidant enzymes: preventive effect of pyruvate. Free Radic Res. 2000 Jul33(1):23-30. [Content Brief]