896466-61-8
896466-61-8
Chemical Structure
AT9283 hydrochloride
- CAS No.: 896466-61-8
- Formula:C19H24ClN7O2
- Molecular Weight:417.89
IUPAC Name: 1-cyclopropyl-3-(3-(6-(morpholinomethyl)-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-4-yl)urea hydrochloride
InChIKey: NHFNYIVVGIXBPD-UHFFFAOYSA-N
SMILES: O=C(NC1CC1)NC2=CNN=C2C3=NC(C=C4)=C(C=C4CN5CCOCC5)N3.Cl
Biological Activity: AT9283 hydrochloride is a multi-targeted kinase inhibitor with anti-tumor activity. AT9283 hydrochloride has been found to effectively inhibit Aurora A and Aurora B kinases, thereby affecting cell proliferation and survival. AT9283 hydrochloride can also inhibit several other kinases, including JAK2 and Abl (T315I)[1].
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AT9283 hydrochloride | AT9283 hydrochloride is a multi-targeted kinase inhibitor with anti-tumor activity. AT9283 hydrochloride has been found to effectively inhibit Aurora A and Aurora B kinases, thereby affecting cell proliferation and survival. AT9283 hydrochloride can also inhibit several other kinases, including JAK2 and Abl (T315I). | |||||||||||||||||||||
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