89771-93-7
Chemical Structure
Bilirubin ditaurine
Synonym(s): BR-DT
- CAS No.: 89771-93-7
- Formula:C37H46N6O10S2
- Molecular Weight:798.93
IUPAC Name: 2-(3-(4-methyl-2-((4-methyl-5-((Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-3-(3-oxo-3-((2-sulfoethyl)amino)propyl)-1H-pyrrol-2-yl)methyl)-5-((Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanamido)ethane-1-sulfonic acid
InChIKey: IVYBPZIDQLNIHQ-VYTBREFCSA-N
SMILES: O=S(CCNC(CCC(C(C)=C(N1)/C=C2C(C=C)=C(C(N/2)=O)C)=C1CC3=C(C(C)=C(N3)/C=C4C(C)=C(C(N/4)=O)C=C)CCC(NCCS(=O)(O)=O)=O)=O)(O)=O
Biological Activity: Bilirubin ditaurine (BR-DT) is a peroxyl radical scavenger and chain-breaking antioxidant that inhibits lipid peroxidation by undergoing addition reactions with pyrrole moieties and accelerates copper ion-catalyzed decomposition of lipid hydroperoxides. Bilirubin ditaurine is used in oxidative stress-related research[1][2][3][4].
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Bilirubin ditaurine | Bilirubin ditaurine (BR-DT) is a peroxyl radical scavenger and chain-breaking antioxidant that inhibits lipid peroxidation by undergoing addition reactions with pyrrole moieties and accelerates copper ion-catalyzed decomposition of lipid hydroperoxides. Bilirubin ditaurine is used in oxidative stress-related research. | |||||||||||||||||||||
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References
- [1]. Stocker R, et al. Potential role of conjugated bilirubin and copper in the metabolism of lipid peroxides in bile. Proceedings of the National Academy of Sciences of the United States of America. 1987 Nov;84(22):8130-4. [Content Brief]
- [2]. Arnaout WS, et al. Development of bioartificial liver: bilirubin conjugation in Gunn rats. The Journal of surgical research. 1990 Apr;48(4):379-82.
- [3]. Gordon ER, et al. The isolation and characterization of bilirubin diglucuronide, the major bilirubin conjugate in dog and human bile. The Biochemical journal. 1976 Jun 01;155(3):477-86.
- [4]. Robinson SH, et al. Bilirubin excretion in rats with normal and impaired bilirubin conjugation: effect of phenobarbital. The Journal of clinical investigation. 1971 Dec;50(12):2606-13. [Content Brief]
