898619-81-3
Chemical Structure
Antimicrobial agent-46
- CAS No.: 898619-81-3
- Formula:C6H3N5O3S2
- Molecular Weight:257.25
IUPAC Name: N-(5-nitrothiazol-2-yl)-1,2,3-thiadiazole-4-carboxamide
InChIKey: YZRFPZADHNAXRI-UHFFFAOYSA-N
SMILES: O=C(C1=CSN=N1)NC2=NC=C([N+]([O-])=O)S2
Biological Activity: Antimicrobial agent-46 is a inhibitor of Salmonella typhimurium serine acetyltransferase (StSAT) with an IC50 of 48.6 μM. Antimicrobial agent-46 inhibits bacterial growth in minimal medium lacking cysteine (LB 20%). Antimicrobial agent-46 exerts its effect by targeting the cysteine biosynthesis pathway, which is crucial for bacterial persistence and adaptability. Antimicrobial agent-46 exhibits antibacterial activity against the Gram-negative bacterium Escherichia coli. Antimicrobial agent-46 can be used in infection-related research [1].
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Antimicrobial agent-46 | Antimicrobial agent-46 is a inhibitor of Salmonella typhimurium serine acetyltransferase (StSAT) with an IC50 of 48.6 μM. Antimicrobial agent-46 inhibits bacterial growth in minimal medium lacking cysteine (LB 20%). Antimicrobial agent-46 exerts its effect by targeting the cysteine biosynthesis pathway, which is crucial for bacterial persistence and adaptability. Antimicrobial agent-46 exhibits antibacterial activity against the Gram-negative bacterium Escherichia coli. Antimicrobial agent-46 can be used in infection-related research . | |||||||||||||||||||||
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