898743-92-5
898743-92-5
Chemical Structure
DSM74
- CAS No.: 898743-92-5
- Formula:C13H10F3N5
- Molecular Weight:293.25
IUPAC Name: 5-methyl-N-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
InChIKey: LRHHXKBKRNNFRV-UHFFFAOYSA-N
SMILES: FC(F)(F)C1=CC=C(C=C1)NC2=CC(C)=NC3=NC=NN23
Biological Activity: DSM74 (compound 21) is an orally active and potent antimalarial inhibitor of PfDHODH (IC50=0.28 μM) and PbDHODH (IC50=0.38 μM). DSM74 inhibits the growth of Plasmodium in animals[1].
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DSM74 | DSM74 (compound 21) is an orally active and potent antimalarial inhibitor of PfDHODH (IC50=0.28 μM) and PbDHODH (IC50=0.38 μM). DSM74 inhibits the growth of Plasmodium in animals. | |||||||||||||||||||||
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