898911-09-6
Chemical Structure
DRL-17822
- CAS No.: 898911-09-6
- Formula:C30H31F6N7
- Molecular Weight:603.60
InChIKey: OCNBSSLDAIWTKS-UHFFFAOYSA-N
SMILES: FC(F)(C1=CC(CN(CC2=CC3=C(N=C2N(CC4CC4)CC5CC5)C(C)=CC=C3)C6=NN(C)N=N6)=CC(C(F)(F)F)=C1)F
Biological Activity: DRL-17822 is a selective cholesteryl ester transfer protein (CETP) inhibitor. DRL-17822 increases high-density lipoprotein levels. The exposure of DRL-17822 nanocrystal formulation increases significantly after a high-fat breakfast. The exposure of DRL-17822 in the fasted state is higher than that of its nanocrystal formulation. DRL-17822 can be used in the research of type II hyperlipidemia and atherosclerotic cardiovascular disease[1].
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DRL-17822 | DRL-17822 is a selective cholesteryl ester transfer protein (CETP) inhibitor. DRL-17822 increases high-density lipoprotein levels. The exposure of DRL-17822 nanocrystal formulation increases significantly after a high-fat breakfast. The exposure of DRL-17822 in the fasted state is higher than that of its nanocrystal formulation. DRL-17822 can be used in the research of type II hyperlipidemia and atherosclerotic cardiovascular disease. | |||||||||||||||||||||
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