899789-84-5
899789-84-5
Chemical Structure
TPα/β antagonist-1
- CAS No.: 899789-84-5
- Formula:C20H23N3O6S
- Molecular Weight:433.48
InChIKey: IDPWSIWQGCMVFU-UHFFFAOYSA-N
SMILES: O=C(NC1CCCCC1)NS(=O)(C2=CC([N+]([O-])=O)=CC=C2OC3=CC=C(C=C3)C)=O
Biological Activity: TPα/β antagonist-1 is a TXA2 receptor α (TPα) and TPβ antagonist with IC50s of 1.52 nM and 0.79 nM, respectively. TPα/β antagonist-1 inhibits U-46619 (HY-108566)-induced intracellular calcium mobilization, and imhibits platelet aggregation. TPα/β antagonist-1 can be used for the research of cardiovascular disease[1].
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TPα/β antagonist-1 | TPα/β antagonist-1 is a TXA2 receptor α (TPα) and TPβ antagonist with IC50s of 1.52 nM and 0.79 nM, respectively. TPα/β antagonist-1 inhibits U-46619 (HY-108566)-induced intracellular calcium mobilization, and imhibits platelet aggregation. TPα/β antagonist-1 can be used for the research of cardiovascular disease. | |||||||||||||||||||||
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