90-65-3
90-65-3
Chemical Structure
Penicillic acid
- CAS No.: 90-65-3
- Formula:C8H10O4
- Molecular Weight:170.16
IUPAC Name: (Z)-3-methoxy-5-methyl-4-oxohexa-2,5-dienoic acid
InChIKey: VOUGEZYPVGAPBB-XQRVVYSFSA-N
SMILES: C=C(C)C(/C(OC)=C/C(O)=O)=O
Biological Activity: Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro. Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Penicillic acid | 99.63% | Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro. Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8. | ||||||||||||||||||||
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Penicillic acid (Standard) | ≥98% | Penicillic acid (Standard) is the analytical standard of Penicillic acid (HY-N6777). This product is intended for research and analytical applications. Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro. Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8. | ||||||||||||||||||||
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Penicillic acid-13C8 | Penicillic acid-13C8 is the 13C-labeled Penicillic acid (HY-N6777). Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro. Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8. | |||||||||||||||||||||
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References
- [1]. Sorenson WG, et al. Toxicity of penicillic acid for rat alveolar macrophages in vitro. Environ Res. 1986 Dec;41(2):505-13. [Content Brief]
- [2]. Bando M, et al. The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complex. J Biol Chem. 2003 Feb 21;278(8):5786-93. [Content Brief]
