9012-37-7
Chemical Structure
Aminoacylase
Synonym(s): Acylase I
- CAS No.: 9012-37-7
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Aminoacylase]
Biological Activity: Aminoacylase (Acylase I) is a long acyl-chain metal-dependent hydrolase and N-acyltransferase. Aminoacylase catalyzes the hydrolysis of the amide bond of N-acyl-L-amino acids as well as the N-acylation of L-amino acids with fatty acids. Mammalian Aminoacylase is involved in the catabolism of acetylated peptides or acetylated amino acids and in the detoxification of xenobiotics. Aminoacylase is also an enzyme with industrial application value, and can be used for the hydrolysis and synthesis of N-acyl amino acids[1][2].
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Aminoacylase | Aminoacylase (Acylase I) is a long acyl-chain metal-dependent hydrolase and N-acyltransferase. Aminoacylase catalyzes the hydrolysis of the amide bond of N-acyl-L-amino acids as well as the N-acylation of L-amino acids with fatty acids. Mammalian Aminoacylase is involved in the catabolism of acetylated peptides or acetylated amino acids and in the detoxification of xenobiotics. Aminoacylase is also an enzyme with industrial application value, and can be used for the hydrolysis and synthesis of N-acyl amino acids. | |||||||||||||||||||||
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References
- [1]. Haeger G, et al. Novel recombinant aminoacylase from Paraburkholderia monticola capable of N-acyl-amino acid synthesis. Applied microbiology and biotechnology. 2024 Dec;108(1):93. [Content Brief]
- [2]. Kallure GS, et al. Aminoacylase efficiently hydrolyses fatty acid amino acid conjugates of Helicoverpa armigera potentially to increase the pool of glutamine. Insect biochemistry and molecular biology. 2024 Feb;165:104070.