902940-64-1
Chemical Structure
C791-0064
- CAS No.: 902940-64-1
- Formula:C27H34N4O2S
- Molecular Weight:478.65
IUPAC Name: N-(3-([1,4'-bipiperidin]-1'-yl)propyl)-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide
InChIKey: SAVFOJHPVRSLGC-UHFFFAOYSA-N
SMILES: O=C(C1=CC(NC(C2=CC=CC=C2S3)=O)=C3C=C1)NCCCN(CC4)CCC4N5CCCCC5
Biological Activity: C791-0064 is a RAD52 inhibitor. C791-0064 specifically binds to RAD52 and disrupts its single-strand annealing activity. C791-0064 specifically inhibits the proliferation of cancer cells with BRCA2 deficiency, inducing DNA damage and apoptosis (apoptosis). C791-0064 can be used for the study of BRCA mutation-related cancers (such as breast cancer and ovarian cancer)[1].
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C791-0064 | 99.15% | C791-0064 is a RAD52 inhibitor. C791-0064 specifically binds to RAD52 and disrupts its single-strand annealing activity. C791-0064 specifically inhibits the proliferation of cancer cells with BRCA2 deficiency, inducing DNA damage and apoptosis (apoptosis). C791-0064 can be used for the study of BRCA mutation-related cancers (such as breast cancer and ovarian cancer). | ||||||||||||||||||||
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