90411-13-5
Chemical Structure
Neochamaejasmine A
- CAS No.: 90411-13-5
- Formula:C30H22O10
- Molecular Weight:542.49
IUPAC Name: (2S,2'S,3S,3'S)-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bichromane]-4,4'-dione
InChIKey: RNQBLQALVMHBKH-OIWKEWRZSA-N
SMILES: O=C1[C@]([C@@]2([H])[C@@H](C3=CC=C(C=C3)O)OC4=CC(O)=CC(O)=C4C2=O)([H])[C@@H](C5=CC=C(C=C5)O)OC6=CC(O)=CC(O)=C61
Biological Activity: Neochamaejasmine A is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L.. Neochamaejasmine A inhibits proliferation, induces cell cycle arrest and apoptosis in tumor cells. Neochamaejasmine A can be used in the research of cancers such as prostate cancer, hepatoma cancer[1][2].
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Neochamaejasmine A | Neochamaejasmine A is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L.. Neochamaejasmine A inhibits proliferation, induces cell cycle arrest and apoptosis in tumor cells. Neochamaejasmine A can be used in the research of cancers such as prostate cancer, hepatoma cancer. | |||||||||||||||||||||
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References
- [1]. Liu WK, et al. Involvement of p21 and FasL in induction of cell cycle arrest and apoptosis by neochamaejasmin A in human prostate LNCaP cancer cells. J Nat Prod. 2008 May;71(5):842-6. [Content Brief]
- [2]. Ding Y, et al. Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway. Oxid Med Cell Longev. 2020 Jan 20;2020:3237150. [Content Brief]
