90520-42-6
Chemical Structure
LND 623
- CAS No.: 90520-42-6
- Formula:C27H47NO6
- Molecular Weight:481.67
IUPAC Name: (2R,3R,4R,5R,6S)-2-(((3R,5S,8R,9S,10S,13R,14R,17S)-14-amino-17-((R)-1-hydroxyethyl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol
InChIKey: RHGPTBMIKFUPQA-QXTIEUCESA-N
SMILES: O[C@H]([C@@H]([C@H]([C@H](C)O1)O)O)[C@H]1O[C@H]2CC[C@]3(C)[C@@]4([H])CC[C@]5(C)[C@@H]([C@H](O)C)CC[C@]5(N)[C@]4([H])CC[C@]3([H])C2
Biological Activity: LND 623 is an inotropic aminosteroid with positive inotropic properties. LND 623 inhibits Na+/K+ ATPase activity. The LD50 of LND 623 infused i.v. is around 45 mg/kg, a value ten times higher than the LD50 for Ouabain (HY-B1457)[1].
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LND 623 | LND 623 is an inotropic aminosteroid with positive inotropic properties. LND 623 inhibits Na+/K+ ATPase activity. The LD50 of LND 623 infused i.v. is around 45 mg/kg, a value ten times higher than the LD50 for Ouabain (HY-B1457). | |||||||||||||||||||||
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