90614-49-6
90614-49-6
Chemical Structure
Diprotin B
- CAS No.: 90614-49-6
- Formula:C16H29N3O4
- Molecular Weight:327.42
IUPAC Name: L-valyl-L-prolyl-L-leucine
InChIKey: NHXZRXLFOBFMDM-AVGNSLFASA-N
SMILES: CC(C)C[C@@H](C(O)=O)NC([C@H]1N(C([C@H](C(C)C)N)=O)CCC1)=O
Biological Activity: Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Diprotin B | 99.68% | Diprotin B is a dipeptidyl aminopeptidase IV (DPP IV) inhibitor. The apparent competitive inhibition of DPP-IV by the diprotins is a kinetic artifact, derived from the substrate-like nature of tripeptides containing a penultimate proline residue. | ||||||||||||||||||||
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References
- [1]. Rahfeld J, et al. Are diprotin A (Ile-Pro-Ile) and diprotin B (Val-Pro-Leu) inhibitors or substrates of dipeptidyl peptidase IV? Biochim Biophys Acta. 1991 Jan 29;1076(2):314-6. [Content Brief]
- [2]. Hatanaka T, et al. Inhibitory effect of collagen-derived tripeptides on dipeptidylpeptidase-IV activity. J Enzyme Inhib Med Chem. 2014 Dec;29(6):823-8. [Content Brief]
