907589-02-0
907589-02-0
Chemical Structure
Ac-DMQD-pNA
- CAS No.: 907589-02-0
- Formula:C26H35N7O12S
- Molecular Weight:669.66
InChIKey: LHKPPRWOHBASDX-VJANTYMQSA-N
SMILES: O=C(C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NC1=CC=C(C=C1)[N+]([O-])=O)=O)CC(O)=O)=O)CCC(N)=O)=O)CCSC)=O)CC(O)=O
Biological Activity: Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006)[1][2].
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Ac-DMQD-pNA | Ac-DMQD-pNA is a peptide substrate. Both of the recombinant CgCaspase-1 (rCgCaspase-1) and the C-terminus of CgCaspase-1 (rCgCaspase-1-C) exhibits similar caspase activity towards proteolytic substrate Ac-DMQD-pNA and Ac-DEVD-pNA (HY-P1006). | |||||||||||||||||||||
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References
- [1]. Fang B, et al. Structural and kinetic analysis of caspase-3 reveals role for s5 binding site in substrate recognition. J Mol Biol. 2006 Jul 14;360(3):654-66. [Content Brief]
- [2]. Lu G, et al. The self-activation and LPS binding activity of executioner caspase-1 in oyster Crassostrea gigas. Dev Comp Immunol. 2017 Dec;77:330-339. [Content Brief]
