908510-73-6
Chemical Structure
Rev1-CT/RIR PPI-IN-1
- CAS No.: 908510-73-6
- Formula:C21H29N3O3S
- Molecular Weight:403.54
IUPAC Name: 1-acetyl-N-(3-(cyclopropylcarbamoyl)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)piperidine-4-carboxamide
InChIKey: OAIQWJVXBJTNAL-UHFFFAOYSA-N
SMILES: O=C(C1CCN(C(C)=O)CC1)NC2=C(C(NC3CC3)=O)C(CCC(C)C4)=C4S2
Biological Activity: Rev1-CT/RIR PPI-IN-1 (Compound 1) is a thiophene-based compound. Rev1-CT/RIR PPI-IN-1 can specifically disrupt the protein-protein interaction between Rev1-CT and RIR, with an IC50 value of 2.5 µM. Rev1-CT/RIR PPI-IN-1 can enhance chemosensitivity and reduce the mutation rate in Cisplatin (HY-17394)-sensitive HT-1080 cells. Rev1-CT/RIR PPI-IN-1 can be used for tumor research[1].
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Rev1-CT/RIR PPI-IN-1 | Rev1-CT/RIR PPI-IN-1 (Compound 1) is a thiophene-based compound. Rev1-CT/RIR PPI-IN-1 can specifically disrupt the protein-protein interaction between Rev1-CT and RIR, with an IC50 value of 2.5 µM. Rev1-CT/RIR PPI-IN-1 can enhance chemosensitivity and reduce the mutation rate in Cisplatin (HY-17394)-sensitive HT-1080 cells. Rev1-CT/RIR PPI-IN-1 can be used for tumor research. | |||||||||||||||||||||
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