911290-20-5
911290-20-5
Chemical Structure
NW-1172 free base
- CAS No.: 911290-20-5
- Formula:C18H16ClNO3
- Molecular Weight:329.78
IUPAC Name: 7-((3-chlorobenzyl)oxy)-4-((methylamino)methyl)-2H-chromen-2-one
InChIKey: JMGUSOLCNQVZCT-UHFFFAOYSA-N
SMILES: O=C1C=C(CNC)C2=CC=C(OCC3=CC=CC(Cl)=C3)C=C2O1
Biological Activity: NW-1172 (free base) (compound 22b) is a 5-HT3 receptor antagonist with performance-enhancing activity in a delayed matching task in monkeys, with the (R) isomer producing more systematic improvements than the (S) isomer, a difference paralleled by the higher affinity of the (R) enantiomer for the 5-HT3 receptor.
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NW-1172 free base | NW-1172 (free base) (compound 22b) is a 5-HT3 receptor antagonist with performance-enhancing activity in a delayed matching task in monkeys, with the (R) isomer producing more systematic improvements than the (S) isomer, a difference paralleled by the higher affinity of the (R) enantiomer for the 5-HT3 receptor. | |||||||||||||||||||||
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