916038-47-6
916038-47-6
Chemical Structure
Pim-1 kinase inhibitor 8
- CAS No.: 916038-47-6
- Formula:C14H17N3O3
- Molecular Weight:275.30
InChIKey: XARGLDJCVPQGEH-UHFFFAOYSA-N
SMILES: N#CC1=C(OCC(N2CCOCC2)=O)N=C(C)C=C1C
Biological Activity: Pim-1 kinase inhibitor 8 is a potent PIM-1 inhibitor with an IC50 value of 14.3 nM. Pim-1 kinase inhibitor 8 impedes cell proliferation and migration through PIM-1 inhibition and the induction of both apoptosis and autophagy. Pim-1 kinase inhibitor 8 inhibits solid tumor growth in Solid Ehrlich Carcinoma (SEC)-bearing mice. Pim-1 kinase inhibitor 8 can be used for breast and liver cancer research[1].
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Pim-1 kinase inhibitor 8 | 99.90% | Pim-1 kinase inhibitor 8 is a potent PIM-1 inhibitor with an IC50 value of 14.3 nM. Pim-1 kinase inhibitor 8 impedes cell proliferation and migration through PIM-1 inhibition and the induction of both apoptosis and autophagy. Pim-1 kinase inhibitor 8 inhibits solid tumor growth in Solid Ehrlich Carcinoma (SEC)-bearing mice. Pim-1 kinase inhibitor 8 can be used for breast and liver cancer research. | ||||||||||||||||||||
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