919992-85-1
919992-85-1
Chemical Structure
BHA536
- CAS No.: 919992-85-1
- Formula:C30H30ClN3O5
- Molecular Weight:548.03
InChIKey: ARAWNHPXQUHVIU-UHFFFAOYSA-N
SMILES: CN(C)CC1=CC2=C(C=C1)C=CC(Cl)=C2C3=C(C4=CNC5=C4C=CC=C5OCCOCCOC)C(NC3=O)=O
Biological Activity: BHA536 is an orally active selective inhibitor for PKCα/β and NF-kB signaling pathway. BHA536 inhibits the proliferation of CD79-mutated ABC DLBCL cell, arrests cell cycle at G1 phase, and induces apoptosis in TMD8 cell. BHA536 exhibits antitumor efficacy in mice[1].
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BHA536 | BHA536 is an orally active selective inhibitor for PKCα/β and NF-kB signaling pathway. BHA536 inhibits the proliferation of CD79-mutated ABC DLBCL cell, arrests cell cycle at G1 phase, and induces apoptosis in TMD8 cell. BHA536 exhibits antitumor efficacy in mice. | |||||||||||||||||||||
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