92085-05-7
92085-05-7
Chemical Structure
5-PT
Synonym(s): 5-Propargyltryptamide
- CAS No.: 92085-05-7
- Formula:C13H14N2O
- Molecular Weight:214.26
InChIKey: DTWYQMFAHVECJC-UHFFFAOYSA-N
SMILES: NCCC1=CNC2=C1C=C(OCC#C)C=C2
Biological Activity: 5-PT (5-Propargyltryptamide) is an alkyne-functionalized 5-HT (HY-B1473A) derivative and serotonylation substrate, taken up by living cells. 5-PT conjugated to a biotin enables identification of serotonylated proteins via copper-click chemistry and mass spectrometry. 5-PT labels and isolates serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT can be used for the research of bronchopulmonary dysplasia[1].
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5-PT | 5-PT (5-Propargyltryptamide) is an alkyne-functionalized 5-HT (HY-B1473A) derivative and serotonylation substrate, taken up by living cells. 5-PT conjugated to a biotin enables identification of serotonylated proteins via copper-click chemistry and mass spectrometry. 5-PT labels and isolates serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT can be used for the research of bronchopulmonary dysplasia. | |||||||||||||||||||||
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