92284-99-6
92284-99-6
Chemical Structure
(E)-Ajoene
- CAS No.: 92284-99-6
- Formula:C9H14OS3
- Molecular Weight:234.40
IUPAC Name: (E)-1-allyl-2-(3-(allylsulfinyl)prop-1-en-1-yl)disulfane
InChIKey: IXELFRRANAOWSF-FNORWQNLSA-N
SMILES: O=S(C/C=C/SSCC=C)CC=C
Biological Activity: (E)-Ajoene is an organosulfur compound and a neuroprotective agent with oral activity. (E)-Ajoene attenuates ischemia/reperfusion-induced hyperactivity, neuronal death in the hippocampal CA1 region, reactive astrogliosis, and reactive microgliosis. (E)-Ajoene is the E isomer of Ajoene (HY-106784) found in oil-macerated garlic products. (E)-Ajoene can be used for research on transient forebrain ischemia[1][2].
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(E)-Ajoene | 95% | (E)-Ajoene is an organosulfur compound and a neuroprotective agent with oral activity. (E)-Ajoene attenuates ischemia/reperfusion-induced hyperactivity, neuronal death in the hippocampal CA1 region, reactive astrogliosis, and reactive microgliosis. (E)-Ajoene is the E isomer of Ajoene (HY-106784) found in oil-macerated garlic products. (E)-Ajoene can be used for research on transient forebrain ischemia. | ||||||||||||||||||||
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References
- [1]. Rakshit D, et al. The Pharmacological Activity of Garlic (Allium sativum) in Parkinson's Disease: From Molecular Mechanisms to the Therapeutic Potential. ACS Chem Neurosci. 2023 Mar 15;14(6):1033-1044. [Content Brief]
- [2]. Yoo DY, et al. Neuroprotective effects of Z-ajoene, an organosulfur compound derived from oil-macerated garlic, in the gerbil hippocampal CA1 region after transient forebrain ischemia. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2014 Oct;72:1-7. [Content Brief]
