923032-38-6
923032-38-6
Chemical Structure
Refametinib (R enantiomer)
Synonym(s): BAY 869766 R enantiomer; RDEA119 R enantiomer
- CAS No.: 923032-38-6
- Formula:C19H20F3IN2O5S
- Molecular Weight:572.34
IUPAC Name: (R)-N-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide
InChIKey: RDSACQWTXKSHJT-LLVKDONJSA-N
SMILES: O=S(C1(C[C@H](CO)O)CC1)(NC(C(NC(C(F)=C2)=CC=C2I)=C3F)=C(OC)C=C3F)=O
Biological Activity: Refametinib R enantiomer is a MEK inhibitor extracted from patent WO2007014011A2, compound 1022, has an EC50 of 2.0-15 nM.
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Refametinib (R enantiomer) | Refametinib R enantiomer is a MEK inhibitor extracted from patent WO2007014011A2, compound 1022, has an EC50 of 2.0-15 nM. | |||||||||||||||||||||
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