923359-38-0
923359-38-0
Chemical Structure
SAR407899
- CAS No.: 923359-38-0
- Formula:C14H16N2O2
- Molecular Weight:244.29
IUPAC Name: 6-(piperidin-4-yloxy)isoquinolin-1(2H)-one
InChIKey: IPEXHQGMTHOKQV-UHFFFAOYSA-N
SMILES: O=C(NC=C1)C(C1=C2)=CC=C2OC3CCNCC3
Biological Activity: SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. SAR407899 shows stable inhibition of migrasome formation.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SAR407899 | 99.67% | SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. SAR407899 shows stable inhibition of migrasome formation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
