923562-23-6
923562-23-6
Chemical Structure
FLT3-IN-2
- CAS No.: 923562-23-6
- Formula:C21H16ClF3N4
- Molecular Weight:416.83
IUPAC Name: 5-((5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl)-N-(4-(trifluoromethyl)benzyl)pyridin-2-amine
InChIKey: MFXPJGJSKHZZGC-UHFFFAOYSA-N
SMILES: FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=C(Cl)C=C43)C=C2)C=C1)(F)F
Biological Activity: FLT3-IN-2 (Compound P-0266) is a FLT3 inhibitor with an IC50 of < 1 μM. FLT3-IN-2 can be used in acute myeloid leukemia research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FLT3-IN-2 | 98.80% | FLT3-IN-2 (Compound P-0266) is a FLT3 inhibitor with an IC50 of < 1 μM. FLT3-IN-2 can be used in acute myeloid leukemia research. | ||||||||||||||||||||
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References
- [1]. Zhang, Chao, et al. Kinase modulation for the treatment of leukemias. From PCT Int. Appl. (2012), WO 2012158957 A2 20121122.
- [2]. Zhang Chao, et al. 7-Azaindole derivatives and their preparation, pharmaceutical compositions and use for modulating c-kit and c-fms activity. From PCT Int. Appl. (2007), WO 2007013896 A2 20070201.
