924759-42-2
924759-42-2
Chemical Structure
BT44
- CAS No.: 924759-42-2
- Formula:C28H27F4N3O4S
- Molecular Weight:577.59
IUPAC Name: (4-(5-((3,4-dihydroisoquinolin-2(1H)-yl)sulfonyl)-2-methoxyphenyl)piperazin-1-yl)(4-fluoro-2-(trifluoromethyl)phenyl)methanone
InChIKey: MFQBJWVTKPJNEP-UHFFFAOYSA-N
SMILES: O=C(N1CCN(CC1)C2=CC(S(=O)(N3CC4=C(CC3)C=CC=C4)=O)=CC=C2OC)C5=CC=C(C=C5C(F)(F)F)F
Biological Activity: BT44 is a selective RET activator. BT44 can penetrate through the blood-brain barrier and can be used for the research of neurodegenerative disorders and diabetes mellitus[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BT44 | 98.87% | BT44 is a selective RET activator. BT44 can penetrate through the blood-brain barrier and can be used for the research of neurodegenerative disorders and diabetes mellitus. | ||||||||||||||||||||
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References
- [1]. Viisanen H, et al. Novel RET agonist for the treatment of experimental neuropathies. Mol Pain. 2020 Jan-Dec;16:1744806920950866. [Content Brief]
- [2]. Renko JM, et al. Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats. J Parkinsons Dis. 2021;11(3):1023-1046. [Content Brief]
