925701-88-8
925701-88-8
Chemical Structure
Acitretin sodium
Synonym(s): Ro 10-1670 sodium
- CAS No.: 925701-88-8
- Formula:C21H25NaO3
- Molecular Weight:348.41
IUPAC Name: sodium (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoate
InChIKey: ZLNPVBQOHHEBBD-WMOHYEITSA-M
SMILES: CC(/C=C/C(C(C)=CC(OC)=C1C)=C1C)=C\C=C\C(C)=C\C(O[Na])=O
Biological Activity: Acitretin (Ro 10-1670) sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin sodium also can be used for the research of Alzheimer’s disease[1][2][3].
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Acitretin sodium | Acitretin (Ro 10-1670) sodium is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin sodium also can be used for the research of Alzheimer’s disease. | |||||||||||||||||||||
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References
- [1]. Lee CS, et al. A review of acitretin, a systemic retinoid for the treatment of psoriasis. Expert Opin Pharmacother. 2005 Aug;6(10):1725-34. [Content Brief]
- [2]. Seng?r B, et al. Effects of acitretin on spermatogenesis of rats. J Eur Acad Dermatol Venereol. 2006 Jul;20(6):689-92. [Content Brief]
- [3]. Guilherme MDS, et, al. The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients. Front Aging Neurosci. 2019 Jul 23;11:182. [Content Brief]
