928621-15-2
Chemical Structure
Dichlorobenzamil hydrochloride
Synonym(s): 3',4'-Dichlorobenzamil hydrochloride; L-594881 hydrochloride
- CAS No.: 928621-15-2
- Formula:C13H13Cl4N7O
- Molecular Weight:425.10
IUPAC Name: 3,5-diamino-6-chloro-N-(N-(3,4-dichlorobenzyl)carbamimidoyl)pyrazine-2-carboxamide hydrochloride
InChIKey: LPHAOBPPRPXQLQ-UHFFFAOYSA-N
SMILES: O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N.Cl
Biological Activity: Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) hydrochloride is a Na+-Ca2+ Exchanger inhibitor. Dichlorobenzamil (hydrochloride) attenuates the Na+-Ca2+ exchanger-mediated inward current induced by activation of type I metabotropic glutamate receptors in second-order baroreceptor neurons of the rat nucleus tractus solitarius[1].
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Dichlorobenzamil hydrochloride | Dichlorobenzamil (3',4'-Dichlorobenzamil; L-594881) hydrochloride is a Na+-Ca2+ Exchanger inhibitor. Dichlorobenzamil (hydrochloride) attenuates the Na+-Ca2+ exchanger-mediated inward current induced by activation of type I metabotropic glutamate receptors in second-order baroreceptor neurons of the rat nucleus tractus solitarius. | |||||||||||||||||||||
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