928817-42-9
Chemical Structure
Benzylguanine-CY5
- CAS No.: 928817-42-9
- Formula:C46H52N8O8S2
- Molecular Weight:909.08
InChIKey: FZLACSIFEGAVAY-UHFFFAOYSA-N
SMILES: O=C(CCCCCN1C2=CC=C(S(=O)(O)=O)C=C2C(C)(C)/C1=C\C=C\C=C\C3=[N+](CC)C4=C(C3(C)C)C=C(S(=O)([O-])=O)C=C4)NCC5=CC=C(COC6=NC(N)=NC7=C6NC=N7)C=C5
Biological Activity: Benzylguanine-CY5 is a quenched fluorescent dye conjugate based on benzylguanine (BG). Benzylguanine-CY5 possesses the activity of specifically covalently labeling SNAP-tag fusion proteins. Benzylguanine-CY5 exhibits intramolecular fluorescence quenching in the unbound state; upon binding to SNAP-tag, the quenching guanine moiety is cleaved, and its fluorescence intensity increases. Benzylguanine-CY5 can be used for background-free specific fluorescent labeling and imaging studies of SNAP-tag fusion proteins in living cells[1].
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Benzylguanine-CY5 | Benzylguanine-CY5 is a quenched fluorescent dye conjugate based on benzylguanine (BG). Benzylguanine-CY5 possesses the activity of specifically covalently labeling SNAP-tag fusion proteins. Benzylguanine-CY5 exhibits intramolecular fluorescence quenching in the unbound state; upon binding to SNAP-tag, the quenching guanine moiety is cleaved, and its fluorescence intensity increases. Benzylguanine-CY5 can be used for background-free specific fluorescent labeling and imaging studies of SNAP-tag fusion proteins in living cells. | |||||||||||||||||||||
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