931664-41-4
931664-41-4
Chemical Structure
Tec-IN-1
- CAS No.: 931664-41-4
- Formula:C16H15ClN4O2S
- Molecular Weight:362.83
IUPAC Name: 1-(4-acetyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-((6-chloro-1H-imidazo[4,5-b]pyridin-2-yl)thio)ethan-1-one
InChIKey: NWKQXTCDEYJWDS-UHFFFAOYSA-N
SMILES: ClC1=CN=C(N=C(SCC(C2=C(C)C(C(C)=O)=C(C)N2)=O)N3)C3=C1
Biological Activity: Tec-IN-1 (Compound 21) is a Tec inhibitor (IC50s of 11.7 μM). Tec-IN-1 inhibits Tec-mediated tyrosine phosphorylation of FGF2, and inhibits FGF2 secretion from cells[1].
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Tec-IN-1 | Tec-IN-1 (Compound 21) is a Tec inhibitor (IC50s of 11.7 μM). Tec-IN-1 inhibits Tec-mediated tyrosine phosphorylation of FGF2, and inhibits FGF2 secretion from cells. | |||||||||||||||||||||
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