932736-91-9
Chemical Structure
(±)-PPCC hemioxalate
- CAS No.: 932736-91-9
- Formula:C24H29NO3.0.5C2H2O4
- Molecular Weight:424.23
SMILES: O=C([C@@]1(C2=CC=C(C)C=C2)[C@@H](CN3CCC(C4=CC=CC=C4)(O)CC3)C1)OC.O=C(O)C(O)=O.[0.5]
Biological Activity: (±)-PPCC hemioxalate is a compound that has the ability to regulate the activity of the sigma-1 receptor. (±)-PPCC hemioxalate can selectively bind sigma-1 protein (s1), and then activate s1 receptor leading to dissociation of s1-BIP complex to regulate ER-mitochondrial calcium signaling, which plays an important role in cell bioenergy and cell survival. (±)-PPCC hemioxalate can be used to study sigma-1 receptors in cocaine addiction, forgetting, pain, depression, Alzheimer's disease, stroke, and cancer[1].
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(±)-PPCC hemioxalate | (±)-PPCC hemioxalate is a compound that has the ability to regulate the activity of the sigma-1 receptor. (±)-PPCC hemioxalate can selectively bind sigma-1 protein (s1), and then activate s1 receptor leading to dissociation of s1-BIP complex to regulate ER-mitochondrial calcium signaling, which plays an important role in cell bioenergy and cell survival. (±)-PPCC hemioxalate can be used to study sigma-1 receptors in cocaine addiction, forgetting, pain, depression, Alzheimer's disease, stroke, and cancer. | |||||||||||||||||||||
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