934235-44-6
934235-44-6
Chemical Structure
Robatumumab
Synonym(s): Sch 717454; 19D12
- CAS No.: 934235-44-6
- Formula:N/A
- Molecular Weight:(146.36 kDa)
IUPAC Name: tert-butyl (2-cyano-4-(trifluoromethyl)phenyl)carbamate
SMILES: [Robatumumab]
Biological Activity: Robatumumab (Sch 717454) is an anti-human IGF-1R (insulin-like growth factor receptor-1) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Robatumumab | 99.36% | Robatumumab (Sch 717454) is an anti-human IGF-1R (insulin-like growth factor receptor-1) antibody. Robatumumab shows anti-tumor activity and anti-proliferative activity to cancer cells. Robatumumab can be used in osteosarcoma and Ewing sarcoma research. | ||||||||||||||||||||
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References
- [1]. Anderson PM, et al. A phase II study of clinical activity of SCH 717454 (robatumumab) in patients with relapsed osteosarcoma and Ewing sarcoma. Pediatr Blood Cancer. 2016 Oct;63(10):1761-70. [Content Brief]
- [2]. Wang Y, et al. A fully human insulin-like growth factor-I receptor antibody SCH 717454 (Robatumumab) has antitumor activity as a single agent and in combination with cytotoxics in pediatric tumor xenografts. Mol Cancer Ther. 2010 Feb;9(2):410-8. [Content Brief]
