936350-00-4
936350-00-4
Chemical Structure
Fiboflapon
Synonym(s): GSK2190915; AM-803
- CAS No.: 936350-00-4
- Formula:C38H43N3O4S
- Molecular Weight:637.83
IUPAC Name: 3-(3-(tert-butylthio)-1-(4-(6-ethoxypyridin-3-yl)benzyl)-5-((5-methylpyridin-2-yl)methoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid
InChIKey: DFQGDHBGRSTTHX-UHFFFAOYSA-N
SMILES: CC(C(O)=O)(C)CC1=C(SC(C)(C)C)C2=CC(OCC3=CC=C(C)C=N3)=CC=C2N1CC4=CC=C(C5=CN=C(OCC)C=C5)C=C4
Biological Activity: Fiboflapon (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fiboflapon | 99.50% | Fiboflapon (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood. | ||||||||||||||||||||
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