938067-78-8
938067-78-8
Chemical Structure
GTX-758
Synonym(s): Capesaris
- CAS No.: 938067-78-8
- Formula:C19H13F2NO3
- Molecular Weight:341.31
IUPAC Name: 3-fluoro-N-(4-fluorophenyl)-4-hydroxy-N-(4-hydroxyphenyl)benzamide
InChIKey: FBCQEUMZZNVQKD-UHFFFAOYSA-N
SMILES: O=C(N(C1=CC=C(F)C=C1)C2=CC=C(O)C=C2)C3=CC=C(O)C(F)=C3
Biological Activity: GTX-758 is an orally active, nonsteroidal, selective agonist of ERα. GTX-758 plays an important role in castration resistant prostate cancer (CRPC) research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GTX-758 | 99.59% | GTX-758 is an orally active, nonsteroidal, selective agonist of ERα. GTX-758 plays an important role in castration resistant prostate cancer (CRPC) research. | ||||||||||||||||||||
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α-Synuclein inhibitor 4 | α-Synuclein inhibitor 4 (compound 3gh) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 0.98 μM and inhibition ratio at 30 μM of 91.2%. | |||||||||||||||||||||
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α-Synuclein inhibitor 6 | α-Synuclein inhibitor 6 (compound 3ge) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.70 μM and inhibition ratio at 30 μM of 94.4%. | |||||||||||||||||||||
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Succinate dehydrogenase-IN-5 | 98.26% | Succinate dehydrogenase-IN-5 (Compound M8) is the inhibitor for succinate dehydrogenase. Succinate dehydrogenase-IN-5 interfers with the energy metabolism and growth of fungi, inhibits Rhizoctonia solani, Sclerotinia sclerotiorum, Botrytis cinerea and Fusarium graminearum with EC50 < 0.3 μg/mL. | ||||||||||||||||||||
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α-Synuclein-IN-22 | α-Synuclein-IN-22 is an α-Synuclein inhibitor with an IC50 of 2.7 μM against human α-Syn. α-Synuclein-IN-22 exerts anti-aggregation effects by stabilizing the native conformation of α-Syn, inhibiting the formation of β-sheet aggregates and inclusion bodies, and dissociating mature fibrils into functional monomers. α-Synuclein-IN-22 scavenges ROS and shows low cytotoxicity. α-Synuclein-IN-22 can be used in research related to Parkinson's disease. | |||||||||||||||||||||
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α-Synuclein-IN-23 | α-Synuclein-IN-23 is an inhibitor of α-synuclein with an IC50 of 2.1 μM. α-Synuclein-IN-23 dissociates preformed α-synuclein aggregates, scavenges reactive oxygen species (ROS), and inhibits the formation of α-synuclein inclusions in neuronal cells. α-Synuclein-IN-23 can be used for the research of Parkinson's disease. | |||||||||||||||||||||
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α-Synuclein-IN-24 | α-Synuclein-IN-24 is an α-synuclein (α-Syn) aggregation inhibitor with an IC50 of 4.0 μM. α-Synuclein-IN-24 stabilizes the secondary conformation of α-synuclein monomers, inhibits β-sheet formation, reduces oligonucleation during the aggregation lag phase, dissociates preformed aggregates, and blocks reaggregation. α-Synuclein-IN-24 reduces α-synuclein inclusions in neuronal cells and scavenges ROS. α-Synuclein-IN-24 can be used for the research of Parkinson's disease. | |||||||||||||||||||||
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ER ligand-10 | ER ligand-10 (Compound 11a) is a weak ERa and ERβ ligand, and shows weak estrogenic activity. | |||||||||||||||||||||
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4,4'-(Phenylazanediyl)dibenzoic acid | 4,4'-(Phenylazanediyl)dibenzoic acid (Diphenylamin-4,4'-dicarbonsaeure) is a metal-organic framework (MOF). | |||||||||||||||||||||
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4,4′-[[(4-Carboxyphenyl)methyl]imino]bis[benzoic acid] | 4,4′-[[(4-Carboxyphenyl)methyl]imino]bis[benzoic acid] is a metal-organic framework (MOF). | |||||||||||||||||||||
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Tris(4-fluorophenyl)amine | Tris(4-fluorophenyl)amine is a metal-organic framework (MOF). | |||||||||||||||||||||
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