940061-39-2
Chemical Structure
OB-24 free base
- CAS No.: 940061-39-2
- Formula:C15H17BrN2O2
- Molecular Weight:337.21
InChIKey: AKRPSFVFWQTUDK-UHFFFAOYSA-N
SMILES: BrC1=CC=C(CCC2(CN3C=NC=C3)OCCO2)C=C1
Biological Activity: OB-24 free base is a compound that potently and selectively inhibits heme oxygenase 1 (HO-1) and has the potential to inhibit advanced prostate cancer. OB-24 significantly reduces protein carbonylation and the formation of reactive oxygen species by selectively inhibiting HO-1 activity in prostate cancer cells. OB-24 significantly inhibited cell proliferation in vitro and inhibited tumor growth and lymph node and lung metastasis in vivo. OB-24 exhibits powerful synergy when used in combination with Taxol[1].
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OB-24 free base | OB-24 free base is a compound that potently and selectively inhibits heme oxygenase 1 (HO-1) and has the potential to inhibit advanced prostate cancer. OB-24 significantly reduces protein carbonylation and the formation of reactive oxygen species by selectively inhibiting HO-1 activity in prostate cancer cells. OB-24 significantly inhibited cell proliferation in vitro and inhibited tumor growth and lymph node and lung metastasis in vivo. OB-24 exhibits powerful synergy when used in combination with Taxol. | |||||||||||||||||||||
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