941987-60-6
941987-60-6
Chemical Structure
H-151
- CAS No.: 941987-60-6
- Formula:C17H17N3O
- Molecular Weight:279.34
IUPAC Name: 1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea
InChIKey: UJZDIKVQFMCLBE-UHFFFAOYSA-N
SMILES: O=C(NC1=CNC2=C1C=CC=C2)NC3=CC=C(CC)C=C3
Biological Activity: H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H-151 can be used for the research of autoinflammatory disease[1].
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H-151 | 99.78% | H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H-151 can be used for the research of autoinflammatory disease. | ||||||||||||||||||||
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H-151 (Standard) | ≥98% | H-151 (Standard) is the analytical standard of H-151 (HY-112693). This product is intended for research and analytical applications. H-151 is a potent, selective and covalent antagonist of STING that has noteworthy inhibitory activity both in cells and in vivo. H-151 reduces TBK1 phosphorylation and suppresses STING palmitoylation. H-151 can be used for the research of autoinflammatory disease. | ||||||||||||||||||||
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