94457-09-7
94457-09-7
Chemical Structure
KC-764
- CAS No.: 94457-09-7
- Formula:C14H15N3O
- Molecular Weight:241.29
IUPAC Name: (2-methylpyrazolo[1,5-a]pyridin-3-yl)(1,4,5,6-tetrahydropyridin-3-yl)methanone
InChIKey: SLMUMPSLUWOXAO-UHFFFAOYSA-N
SMILES: O=C(C1=C2C=CC=CN2N=C1C)C3=CNCCC3
Biological Activity: KC-764 is an orally active, reversible cyclooxygenase inhibitor with relative selectivity for platelet cyclooxygenase. KC-764 inhibits platelet thromboxane A2 (TXA2) production and platelet aggregation, with IC50s of 0.23 μM and 26 nM, respectively. KC-764 can be used for the research on antiplatelet and recurrence prevention in ischemic stroke[1].
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KC-764 | KC-764 is an orally active, reversible cyclooxygenase inhibitor with relative selectivity for platelet cyclooxygenase. KC-764 inhibits platelet thromboxane A2 (TXA2) production and platelet aggregation, with IC50s of 0.23 μM and 26 nM, respectively. KC-764 can be used for the research on antiplatelet and recurrence prevention in ischemic stroke. | |||||||||||||||||||||
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