944726-62-9
Chemical Structure
Thailandolide B
- CAS No.: 944726-62-9
- Formula:C27H34O8
- Molecular Weight:486.55
IUPAC Name: (1R,2R,7aR,8S,9aR,13aS,13bR)-5,8-dihydroxy-2,7a,10,10,13a-pentamethyl-4,11-dioxo-1,7a,8,9,9a,10,11,12,13,13a,13b,14-dodecahydro-2H,4H-benzo[a]pyrano[3,4-j]xanthen-1-yl acetate
InChIKey: WBVYOHUPTWNRJD-ZLQXHUGPSA-N
SMILES: C[C@@]12[C@]3([H])[C@@](OC4=CC(O)=C(C(O[C@@H]([C@@H]5OC(C)=O)C)=O)C5=C4C3)([C@H](C[C@@]1([H])C(C)(C(CC2)=O)C)O)C
Biological Activity: Thailandolide B is a merodrimane-type meroterpenoid fungal (fungal) metabolite that exhibits insecticidal activity against silkworm (Bombyx mori) larvae (LD50 = 10 μg/g diet). Thailandolide B can be used in research on insecticidal natural products[1][2][3][4][5][6].
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Thailandolide B | Thailandolide B is a merodrimane-type meroterpenoid fungal (fungal) metabolite that exhibits insecticidal activity against silkworm (Bombyx mori) larvae (LD50 = 10 μg/g diet). Thailandolide B can be used in research on insecticidal natural products. | |||||||||||||||||||||
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References
- [1]. Dethoup T, et al. Merodrimanes and other constituents from Talaromyces thailandiasis. Journal of natural products. 2007 Jul;70(7):1200-2.
- [2]. El-Elimat T, et al. Coumarins, dihydroisocoumarins, a dibenzo-α-pyrone, a meroterpenoid, and a merodrimane from Talaromyces amestolkiae. Tetrahedron Lett. 2021 May 25;72:153067.
- [3]. Hayashi H, et al. A new meroterpenoid, chrodrimanin C, from YO-2 of Talaromyces sp. Bioscience, biotechnology, and biochemistry. 2012;76(4):745-8.
- [4]. Hayashi H, et al. New chrodrimanin congeners, chrodrimanins D-H, from YO-2 of Talaromyces sp. Bioscience, biotechnology, and biochemistry. 2012;76(9):1765-8.
- [5]. Kuml D, et al. Spiculisporic acid E, a new spiculisporic acid derivative and ergosterol derivatives from the marine-sponge associated fungus Talaromyces trachyspermus (KUFA 0021). Natural product communications. 2014 Aug;9(8):1147-50.
- [6]. Nonaka K, et al. Induced production of BE-31405 by co-culturing of Talaromyces siamensis FKA-61 with a variety of fungal strains. The Journal of antibiotics. 2015 Sep;68(9):573-8. [Content Brief]
