945635-15-4
945635-15-4
Chemical Structure
Deferitazole
Synonym(s): FBS 0701
- CAS No.: 945635-15-4
- Formula:C18H25NO7S
- Molecular Weight:399.46
IUPAC Name: (S)-2-(2-hydroxy-3-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)phenyl)-4-methyl-4,5-dihydrothiazole-4-carboxylic acid
InChIKey: AWHIMFSHNAAMBM-GOSISDBHSA-N
SMILES: O=C([C@]1(C)N=C(C2=CC=CC(OCCOCCOCCOC)=C2O)SC1)O
Biological Activity: Deferitazole (FBS 0701) is an orally active iron chelator. Deferitazole shows antimalarial activity and Can be used for study of malaria [1][2].
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Deferitazole | Deferitazole (FBS 0701) is an orally active iron chelator. Deferitazole shows antimalarial activity and Can be used for study of malaria . | |||||||||||||||||||||
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References
- [1]. Hider RC, et al. Deferitazole, a new orally active iron chelator. Dalton Trans. 2015;44(11):5197-5204. [Content Brief]
- [2]. Ferrer P, et al. Antimalarial iron chelator, FBS0701, shows asexual and gametocyte Plasmodium falciparum activity and single oral dose cure in a murine malaria model. PLoS One. 2012;7(5):e37171. [Content Brief]
