94596-26-6
![[DPro10] Dynorphin A (1-11), porcine Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-p3647.gif "[DPro10] Dynorphin A (1-11), porcine Chemical Structure")
94596-26-6
Chemical Structure
[DPro10] Dynorphin A (1-11), porcine
- CAS No.: 94596-26-6
- Formula:C63H103N21O13
- Molecular Weight:1362.62
InChIKey: WZHQALIQGVYQGG-DTQUPHKSSA-N
SMILES: OC(C=C1)=CC=C1C[C@H](N)C(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N3[C@H](CCC3)C(N[C@H](C(O)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: [DPro10] Dynorphin A (1-11), porcine, a N-Alkylated derivative, is a potent κ-opioid receptor agonist with a Ki value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine has analgesic property[1][2].
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[DPro10] Dynorphin A (1-11), porcine | [DPro10] Dynorphin A (1-11), porcine, a N-Alkylated derivative, is a potent κ-opioid receptor agonist with a Ki value of 0.13 nM. [DPro10] Dynorphin A (1-11), porcine has analgesic property. | |||||||||||||||||||||
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References
- [1]. Soderstrom K, et, al. N-alkylated derivatives of [D-Pro10]dynorphin A-(1-11) are high affinity partial agonists at the cloned rat kappa-opioid receptor. Eur J Pharmacol. 1997 Nov 5;338(2):191-7. [Content Brief]
- [2]. Gairin JE, et, al. [D-Pro10]-dynorphin(1-11) is a kappa-selective opioid analgesic in mice. J Pharmacol Exp Ther. 1988 Jun;245(3):995-1001. [Content Brief]
