946293-78-3
946293-78-3
Chemical Structure
Aumitin
- CAS No.: 946293-78-3
- Formula:C24H20ClN5O
- Molecular Weight:429.90
IUPAC Name: 2-chloro-N-(4-((4-methyl-6-(phenylamino)pyrimidin-2-yl)amino)phenyl)benzamide
InChIKey: VJNNQBDSUIVCKB-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(NC2=NC(NC3=CC=CC=C3)=CC(C)=N2)C=C1)C4=CC=CC=C4Cl
Biological Activity: Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Aumitin | 99.78% | Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively. | ||||||||||||||||||||
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