946336-44-3
946336-44-3
Chemical Structure
G721-0377
- CAS No.: 946336-44-3
- Formula:C22H25N5O4S
- Molecular Weight:455.53
InChIKey: NDXKDIHHGWRJSS-UHFFFAOYSA-N
SMILES: CC(C)CC1=C(SCC(NC2=CC=C(C(N)=O)C=C2)=O)C3=C(N=C1)N(C)C(N(C)C3=O)=O
Biological Activity: G721-0377 is a CHI3L1 modulator with a human Kd value of 45 μM. G721-0377 binds to CHI3L1 and modulates downstream signaling pathways. G721-0377 suppresses CHI3L1-induced NF-κB activation, decreases secretion of CHI3L1 and IL-6. G721-0377 can be used for the research of Alzheimer's disease[1].
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G721-0377 | G721-0377 is a CHI3L1 modulator with a human Kd value of 45 μM. G721-0377 binds to CHI3L1 and modulates downstream signaling pathways. G721-0377 suppresses CHI3L1-induced NF-κB activation, decreases secretion of CHI3L1 and IL-6. G721-0377 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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