949164-80-1
949164-80-1
Chemical Structure
NP603
- CAS No.: 949164-80-1
- Formula:C26H26N2O5
- Molecular Weight:446.50
IUPAC Name: (Z)-3-(5-((6-(3,5-dimethoxyphenyl)-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrol-3-yl)propanoic acid
InChIKey: ZIZSHSPAAJIYOD-XKZIYDEJSA-N
SMILES: O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC(C4=CC(OC)=CC(OC)=C4)=C3)=O)=C1C
Biological Activity: NP603 is a potent inhibitor of FGF receptor 1, exhibiting remarkable activity against endothelial proliferation in HUVEC cells stimulated by rhFGF-2, with a minimum effective dose of 0.4 microM.
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NP603 | NP603 is a potent inhibitor of FGF receptor 1, exhibiting remarkable activity against endothelial proliferation in HUVEC cells stimulated by rhFGF-2, with a minimum effective dose of 0.4 microM. | |||||||||||||||||||||
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