94978-16-2
Chemical Structure
Saudin
- CAS No.: 94978-16-2
- Formula:C20H22O7
- Molecular Weight:374.38
IUPAC Name: (3aR,3a1S,5S,6aR,7S,9aS,11aR)-5-(furan-3-yl)-3a1,7,11a-trimethylhexahydro-3H-5,9a-epoxyfuro[3,4-f]pyrano[4,3,2-de]chromene-1,8(3a1H,10H)-dione
InChIKey: MIZCOUBLUGPQEO-TWLIFTOHSA-N
SMILES: O=C1OC[C@]23[C@@]1(C)CC[C@]4(O5)[C@@]2(C)[C@@](C[C@](O4)(C6=COC=C6)O3)([H])[C@H](C)C5=O
Biological Activity: Saudin, derived from Clutia lanceolata, is a hypoglycemic compound that significantly enhances glucose-triggered insulin release from murine pancreatic islets. It belongs to a group of new diterpenoids with a distinct tetracyclic core, suggesting potential as a therapeutic agent for diabetes treatment. Proposed biosynthetic pathways outline alternative cyclization routes from a common precursor, with Lanceolide P (16) identified as a promising lead compound for further development in managing diabetes[1].
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Saudin | Saudin, derived from Clutia lanceolata, is a hypoglycemic compound that significantly enhances glucose-triggered insulin release from murine pancreatic islets. It belongs to a group of new diterpenoids with a distinct tetracyclic core, suggesting potential as a therapeutic agent for diabetes treatment. Proposed biosynthetic pathways outline alternative cyclization routes from a common precursor, with Lanceolide P (16) identified as a promising lead compound for further development in managing diabetes. | |||||||||||||||||||||
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